Fresnel zone plates are extensively used as magnifying and focusing optical devices, offering high resolution. They consist of circular gratings with a radially increasing line density. Fresnel zone plates use diffraction instead of reflection or refraction, as in lenses or curved mirrors.
Although transmitted light microscopy techniques, including differential interference contrast (DIC), phase contrast, and polarized microscopy, have improved the visualization of living specimens by enhancing their intrinsic contrast, live imaging using fluorescence microscopy has allowed life science enthusiasts to visualize subcellular structures at higher resolution.
An article published in Advanced Sciences presented hypervalent mannose-binding nanoparticles as efficient targets against against SARS-CoV-2 variants.
Over the years, researchers have tried hard to comprehend topographic signals that promote cell mechanical sensitive responses. The extracellular matrix (ECM) provides a complex cellular microenvironment that controls cellular behavior.