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Researchers decipher enzyme scissors of intestinal microbes

Researchers decipher enzyme scissors of intestinal microbes
sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.

Bernd nidetzky

Researchers decipher enzyme scissors of intestinal microbes

Researchers decipher enzyme scissors of intestinal microbes
phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.

Bernd nidetzkyMartin pfeifferJohannes bitterNature communicationsInstitute of biotechnologyUniversity of grazBiochemical engineeringGraz universityMedical university

Accurate prediction of protein structures and interactions using a three-track neural network

Accurate prediction of protein structures and interactions using a three-track neural network
sciencemag.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencemag.org Daily Mail and Mail on Sunday newspapers.

United statesDoug tischerMareike monscheinNaozumi hiranumaDavide kimBernd nidetzkyDavid juergensEric horvitzDeepmind alphafoldLuki goldschmidtWendy schmidtNational institute of healthGlobal challenges research fundAustrian science fundScience technology facilities councilNational science foundation cyberinfrastructure

RNA basic building block produced biocatalytically for the first time

E-Mail IMAGE: The Graz researchers are the first in the world to demonstrate YeiN , an enzyme that is a suitable biocatalyst for the production of C-nucleosides, the basic building blocks of RNA.. view more Credit: Lunghammer - TU Graz Due to the COVID 19 pandemic and the associated intensive search for therapeutics and vaccines, the chemical substance class of nucleosides is experiencing an enormous increase in interest. Natural and synthetic nucleosides have an antiviral effect and can act as building blocks of ribonucleic acids (RNA). When incorporated into RNA, novel interactions within the macromolecule result with positive consequences for stability and biological effectiveness.

Martin pfeifferBernd nidetzkyNature communicationsAustrian centre of industrial biotechnologyHead of the institute biotechnologyAustrian science fundGraz university of technologyGraz universityAustrian centreIndustrial biotechnologyBioprocess engineeringScientific directorReversec glycosidaseமார்டின் ஃபைஃபர்இயற்கை தகவல்தொடர்புகள்ஆஸ்திரேலிய மையம் ஆஃப் தொழில்துறை உயிரி தொழில்நுட்பவியல்

First enzyme-driven biocatalytic production of nucleic acid building blocks

First enzyme-driven biocatalytic production of nucleic acid building blocks Researchers from TU Graz and acib succeed in the first enzyme-driven biocatalytic synthesis of nucleic acid building blocks. This facilitates the development of antiviral agents and RNA-based therapeutics. Due to the COVID 19 pandemic and the associated intensive search for therapeutics and vaccines, the chemical substance class of nucleosides is experiencing an enormous increase in interest. Natural and synthetic nucleosides have an antiviral effect and can act as building blocks of ribonucleic acids (RNA). When incorporated into RNA, novel interactions within the macromolecule result with positive consequences for stability and biological effectiveness.

Martin pfeifferBernd nidetzkyEmily hendersonNature communicationsAustrian centre of industrial biotechnologyHead of the institute biotechnologyGraz university of technologyGraz universityAustrian centreIndustrial biotechnologyBioprocess engineeringScientific directorமார்டின் ஃபைஃபர்எமிலி ஹென்டர்சன்இயற்கை தகவல்தொடர்புகள்ஆஸ்திரேலிய மையம் ஆஃப் தொழில்துறை உயிரி தொழில்நுட்பவியல்