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This year marks the 100th anniversary of the discovery of insulin, a scientific breakthrough that transformed Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, from a terminal disease into a manageable condition.
Today, Type 2 diabetes is 24 times more prevalent than Type 1. The rise in rates of obesity and incidence of Type 2 diabetes are related and require new approaches, according to University of Arizona researchers, who believe the liver may hold the key to innovative new treatments. All current therapeutics for Type 2 diabetes primarily aim to decrease blood glucose. So, they are treating a symptom, much like treating the flu by decreasing the fever, said Benjamin Renquist, an associate professor in the UArizona College of Agriculture and Life Sciences and BIO5 Institute member. We need another breakthrough.
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United-states
University-of-arizona
Samuel-klein
Benjamin-renquist
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Washington-university-school-of-medicine
Arizona-biomedical-research
Uarizona-college-of-agriculture
Washington-university
New clues point to the liver playing a causal role in type 2 diabetes
New clues point to the liver p.
Researchers hypothesize excess production of a neurotransmitter in the liver could be a causal factor in type 2 diabetes 1/1
Researchers hypothesize excess production of a neurotransmitter in the liver could be a causal factor in type 2 diabetes
Researchers investigating new diabetes treatments believe they have found evidence indicating excess production of a key neurotransmitter in the liver could be a key causal factor in the onset of insulin resistance. The discovery points to novel preventative treatments for type 2 diabetes. Obesity is known to be a cause of type 2 diabetes and, for a long time, we have known that the amount of fat in the liver increases with obesity, says Benjamin Renquist, a University of Arizona researcher working on the project. As fat increases in the liver, the incidence of diabetes increases.
Carolin-geisler
Benjamin-renquist
University-of-arizona
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