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When your mind is the one causing drug side effects

Nocebo effect: When patients worry too much about side effects

Fatigue, palpitations, shortness of breath . and on it goes. The list of possible side effects in a medication package insert can be unsettling. So can a preoperative consultation, when the surgeon informs you of all the risks. The problem is that many patients become fixated on potential complications or adverse reactions - which then may occur for no physiological reason, but because of negative expectations. Doctors call this the nocebo effect, the reverse of the placebo effect whereby expe

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