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We aimed to evaluate the epidemiology of sepsis in secondary and tertiary hospitals in Beijing, China between 2012 and 2018 using information derived from the Beijing Public Health System. The Beijing Public Health System accessed hospital homepage databases and identify patients who diagnosed sepsis or associated condition according to the International Classification of Diseases, 10th Edition, Clinical Modification codes. There are 125 hospitals involved in this study, including 61 secondary hospitals, accounting for 49.2%, and 63 tertiary hospitals, accounting for 50.8%. Patients were stratified by age as minors (0–17 years old), adults (18–64 years old), seniors (65–84 years old), and the elderly (≥ 85 years old). Patient’s demographic information, treatments, outcomes, and all-cause hospitalization cost were evaluated. This study involved 8,597 patients. Patients treated in tertiary hospitals or received blood transfusion decreased with age, whi

United statesWilcoxon kruskal wallisPublic health systemBioethics committeeInternational classification of diseasesBioethics committee of beijing friendshipThird international consensus definitions for sepsisBeijing friendshipBeijing public health systemInternational classificationClinical modificationThird international consensus definitionsSeptic shockTraditional chinese medicine