/PRNewswire/ The Mark Foundation for Cancer Research today announced an alliance with Takeda to accelerate the discovery and development of novel treatments.
MFCR awards new grants to support an emerging approach to cancer therapeutics
The Mark Foundation for Cancer Research (MFCR) has awarded five new grants in support of an important, emerging approach to cancer therapeutics. The projects are centered around the molecular strategy of induced proximity, which involves controlling the physical distance between proteins to regulate or perturb biological processes in the cancer cell.
One of the biggest challenges in developing new cancer therapies is that many proteins are not tractable to the traditional approach in drug discovery of directly inhibiting the function of a therapeutic target. The induced proximity model aims to overcome this hurdle by altering the target protein s function without requiring that small molecules be direct inhibitors.
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NEW YORK - The Mark Foundation for Cancer Research (MFCR) has awarded five new grants in support of an important, emerging approach to cancer therapeutics. The projects are centered around the molecular strategy of induced proximity, which involves controlling the physical distance between proteins to regulate or perturb biological processes in the cancer cell.
One of the biggest challenges in developing new cancer therapies is that many proteins are not tractable to the traditional approach in drug discovery of directly inhibiting the function of a therapeutic target. The induced proximity model aims to overcome this hurdle by altering the target protein s function without requiring that small molecules be direct inhibitors.