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Karolinska Institutet researcher awarded $2 8M NIH Prime grant for drug targeting the opioid systems in alcohol dependence

Dr. Remi Martin-Fardon, Department of Molecular Medicine, The Scripps Research Institute Associate Professor Tijana Jovanović-Talisman, Department of Molecular Medicine, Beckman Research Institute City of Hope, The multidisciplinary team will study how ethanol, the cause of AUD, affects the opioid system function at the molecular, cellular and organism level, using a valid behavioral animal model of AUD, cells in culture, super-resolution fluorescence microscopy imaging and fluorescence correlation spectroscopy. Further Co-PIs of this project are Vladana Vukojevic and Björn Johansson from the Department of Clinical Neuroscience at Karolinska Institutet and Alessandra Matzeu from The Scripps Research Institute. New medications are needed

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