Enterovirus 71 (EV71) is the major pathogen causing severe neurological complications, hand, foot, and mouth disease. The intestinal mucosal immune system has a complete immune response and immune regulation mechanism, consisting of densely arranged monolayer intestinal epithelial cells (IECs) and intestinal intraepithelial lymphocytes (iIELs) distributed among the IECs, which constitute the first line of intestinal mucosa against infection of foreign pathogens. As an enterovirus, EV71 is transmitted by the intestinal tract; however, the mechanisms it uses to evade the immunosurveillance of the intestinal mucosal immune system are still incompletely clarified. The present study investigated how EV71 evades from recognizing and eliminating IECs, iIELs, and iNK cells. We found that EV71 infection-induced higher level of type III interferons (IFN-λ) than type Ⅰ interferons (IFN-β) in IECs and the addition of IFN-λ markedly restricted EV71 replication in IECs. These results indicate t
China working on brain-control weaponry that paralyses and controls opponents dailystar.co.uk - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from dailystar.co.uk Daily Mail and Mail on Sunday newspapers.
Commerce Department sanctions imposed on Chinese technology companies and announced last week revealed that China's military is engaged in dangerous work related to "brain control" warfare research.
The U.S. Commerce Department has added China’s Academy of Military Medical Sciences (AMMS) and 11 of its affiliated research institutes to the Entity List, thereby prohibiting exports,.
The Commerce Department imposed sanctions on Chinese technology companies and announced last week revealed that China's military is engaged in dangerous work related to "brain control" warfare research.