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A pan-approach against blood cancer preserving hematopoiesis

A group of scientists from Basel University Hospital have designed an antibody-drug conjugate (ADC) that eliminated blood cancer cells without attacking healthy hematopoietic stem cells (HSCs), which they modified by base editing and transplanted to renew an altered blood system. They achieved this by focusing on the panhematopoietic marker CD45.

Basel-university-hospital

Cimeio Therapeutics Announces Publication in Nature Demonstrating That CD45 ADC and Shielded HSCs Represent a Potentially Universal Therapy for Blood Cancers

Selective and complete eradication of leukemic cells with an ADC targeting the pan-blood marker CD45 Engineered hematopoietic Stem Cells (HSCs) shielded from the CD45-targeting ADC maintain

Switzerland
Steve-edelson
Lukas-jeker
Stefanie-urlinger
University-of-basel
Cimeio-therapeutics-inc
Basel-university-hospital
Stem-cells
Chief-scientific-officer
Cimeio-therapeutics
Ihr-portfolio

IV Thrombolysis Offers No Benefit for Mild Stroke

Minor ischemic stroke patients with intracranial occlusion should not be treated with IV thrombolysis, a new trial has concluded.

United-kingdom
Finland
Calgary
Alberta
Canada
Italy
Paris
France-general
France
Laquila
Abruzzo
Ireland

Microdosing LSD: Are there benefits? What about risks?

It doesn't take much LSD, short for lysergic acid diethylamide, to substantially alter a person's state of consciousness. Compared with many other substances, the amounts are very small, says Dr Volker Auwärter, director of the forensic toxicology laboratory at the University of Freiburg Medical Centre in Germany: "Upwards of 50, 100 micrograms are said to be a psychedelic dose." The European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) calls the hallucinogen "one of the most potent d

New-zealand
Germany
Auckland
Switzerland
Matthias-liechti
University-of-freiburg-medical-centre
Department-of-biomedicine
Basel-university-hospital
University-of-auckland-school-pharmacy
European-monitoring-centre-for-drugs
Basel-university-psychiatric-clinics
Division-of-clinical-pharmacology

Newly Discovered Virus Kills 'Sleeping' Bacteria - The Good Men Project

Newly Discovered Virus Kills 'Sleeping' Bacteria - The Good Men Project
goodmenproject.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from goodmenproject.com Daily Mail and Mail on Sunday newspapers.

Brussels
Bruxelles-capitale
Belgium
Zurich
Züsz
Switzerland
Basel-stadt
Nina-khanna
Riehen-canton
Enea-maffei
University-of-basel
Basel-university-hospital
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