Introduction: Small bowel intussusception is challenging to diagnose as it does not always declare itself. There is not enough evidence in the literature regarding the management of the same. This case report investigates relevant management options to ensure appropriate and timely treatment. Presenting case: We present a 75-year-old male with a six-week history of abdominal pain and constipation. He has a background history of hypercholesterolaemia, hypertension, asthma, and ex-smoking. He had normal inflammatory markers and an abdominal computerised tomography scan demonstrating dilated jejunal loops with an abrupt transition in the mid-abdomen caused by a short intussusception, with a lead point suggestive of a small mucosal mass. He underwent a diagnostic laparoscopy, which did not demonstrate any obstruction or mass. He had an unremarkable hospital stay and was then discharged home. He remained well on outpatient follow-up. Conclusion: This case highlights the transient nature of
Poster presentation shows treatment with APN401, an autologous cell therapy product targeting the master immune checkpoint Cbl-b, resulted in stabilization.
Since the beginning of the COVID-19 pandemic, in-utero transmission of SARS-CoV-2 remains a rarity and only very few cases have been proven across the world. Here we depict the clinical, laboratory and radiologic findings of preterm triplets born at 28 6/7 weeks to a mother who contracted COVID-19 just one week before delivery. The triplets showed SARS-CoV-2 positivity right after birth, developed significant leukopenia and early-onset pulmonary interstitial emphysema. The most severely affected triplet I required ten days of high-frequency oscillatory ventilation due to failure of conventional invasive ventilation, and circulatory support for four days. Despite a severe clinical course in two triplets (triplet I and III), clinical management without experimental, targeted antiviral drugs was successful. At discharge home, the triplets showed no signs of neurologic or pulmonary sequelae. Placental immunohistology with SARS-CoV-2 N-protein localized strongly to syncytiotrophoblast cells