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First enzyme-driven biocatalytic production of nucleic acid building blocks Researchers from TU Graz and acib succeed in the first enzyme-driven biocatalytic synthesis of nucleic acid building blocks. This facilitates the development of antiviral agents and RNA-based therapeutics. Due to the COVID 19 pandemic and the associated intensive search for therapeutics and vaccines, the chemical substance class of nucleosides is experiencing an enormous increase in interest. Natural and synthetic nucleosides have an antiviral effect and can act as building blocks of ribonucleic acids (RNA). When incorporated into RNA, novel interactions within the macromolecule result with positive consequences for stability and biological effectiveness.

Martin pfeifferBernd nidetzkyEmily hendersonNature communicationsAustrian centre of industrial biotechnologyHead of the institute biotechnologyGraz university of technologyGraz universityAustrian centreIndustrial biotechnologyBioprocess engineeringScientific directorமார்டின் ஃபைஃபர்எமிலி ஹென்டர்சன்இயற்கை தகவல்தொடர்புகள்ஆஸ்திரேலிய மையம் ஆஃப் தொழில்துறை உயிரி தொழில்நுட்பவியல்