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Leap forward in tailored cancer medicine

Scientists trial using gene editing to reprogramme immune systems to target cancer

Scientists have used CRISPR gene editing technology to tailor immune cells to attack tumours, an important step towards personalised cancer treatment.

A decade of CAR-T cell therapy

A decade of CAR-T cell therapy
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Hopes of cancer cure as stunning new therapy trains immune system to hunt and destroy disease

Stunning therapy lands knock-out blow to cancer

While it sounds like the stuff of science fiction, a cancer treatment in which a patient’s own cells are engineered to hunt down and wipe out their disease and then linger in the body to stop the cancer returning is helping to save patients’ lives. The results of the treatment, known as CAR T-cell therapy, have been astonishing.  Patients who had exhausted all other options and been told they had just months to live have gone into remission. Others have even been cured by the one-off dose. In trials, all signs of cancer disappeared in more than 80 per cent of patients with acute lymphoblastic leukaemia the most common cancer in children after receiving CAR T-cells.

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