Researchers from Tokyo Metropolitan University have developed a way to characterize the force generated by contracting myotubes, precursors to skeletal muscle fiber, combining electrostimulation and analysis of wrinkles in the silicone substrate on which they are mounted. Existing methods rely on muscle mass or the expression of certain proteins, both not as strongly correlated with muscle strength. Accurate measurement of myotube strength promises more effective screening of drug targets for treating muscle atrophy.
Researchers develop direct measure for strength of skeletal muscle myotubes
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Less sugar, please! New studies show why diabetics lose muscle mass faster
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Study shows low glucose levels might assist muscle repair ANI | Updated: Apr 03, 2021 12:09 IST
Tokyo [Japan], April 3 (ANI): Less sugar, please! While the high consumption of sugar may increase the risk of obesity, diabetes and heart disease, a recent study has revealed another benefit of keeping sugar at bay.
Researchers from Tokyo Metropolitan University have shown that skeletal muscle satellite cells, key players in muscle repair, proliferate better in low glucose environments.
This is contrary to the conventional wisdom that says mammalian cells fare better when there is more sugar to fuel their activities. Because ultra-low glucose environments do not allow other cell types to proliferate, the team could produce pure cultures of satellite cells, potentially a significant boost for biomedical research.