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IMAGE: Molecular view of a coarse-grained model based on the original structure of M13 major coat proteins view more
Credit: SUTD
Atomistic simulations are a powerful tool to study the movement and interactions of atoms and molecules. In many biological processes, large-scale effects, for example, assembly of large viruses to nanoparticles are important. The assembly processes of these large viruses are of fundamental importance to the design of many devices and viral protein-targeted therapeutics. However, the time and length scale of these assembly processes are usually too large for simulations at molecular resolution.
Moreover, even though an increase in computing power allows for more complex and longer simulations, virus structures, such as M13, are still beyond reach. That is why a research group from the Singapore University of Technology and Design (SUTD) and the Massachusetts Institute of Technology (MIT) has developed a procedure that links large-s
Scientists first to simulate a large-scale virus, M13 phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.