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A Therapeutic Target for High Blood Pressure Control

Yale researchers have identified a potential target for the development of antihypertensive drugs.

United statesDineth karunamuniBrenda cabera mendozaSameet mehtaTrojan rugiraRenato polimantiArya maniLingjuan hongRobertw berlinerSeverin uebbingKushanl gunawardhanaJames noonanCenters for diseaseYale cardiovascular genetics programYale cardiovascular research centerNational institute of health

Yale scientists identify a gene that can repair congenital heart defects

A genetic disorder in PRDM6 causes a common congenital heart defect in premature infants suggesting a potential target for the treatment of congenital heart

United statesKaren hirschiCaroline hendryJinyu liSameet mehtaYinyu wuArya maniVictor gasqueLingjuan hongDavid van dijkAnne eichmannYale school of medicineYale cardiovascular research centerDepartment of medicineNeural crest cellYale school

Yale Researchers Identify Gene That Worsens Fatty Liver Disease

Arya Mani MD, and colleagues have discovered a therapeutic target for the treatment of nonalcoholic fatty liver disease and liver insulin resistance in type 2

Dongyan zhangCarlos fernandez hernandoRichard kibbeyMohsen fathzadehArya maniGerald shulmanDhanpat jainLeigh goedekeHenry ginsbergMario kahnRebeccal cardoneArpita neogiAnand narayananGeorger cowgillNational institute of healthColumbia university

Yale researchers identify gene that worsens fatty liver disease

Arya Mani MD, and colleagues have discovered a therapeutic target for the treatment of nonalcoholic fatty liver disease and liver insulin resistance in type 2

Dongyan zhangCarlos fernandez hernandoRichard kibbeyMohsen fathzadehArya maniGerald shulmanDhanpat jainLeigh goedekeHenry ginsbergMario kahnRebeccal cardoneArpita neogiAnand narayananGeorger cowgillNational institute of healthColumbia university

Genome sequencing identifies variants possibly linked to cardiac rhythm disorder

Genome sequencing identifies variants possibly linked to cardiac rhythm disorder
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Saint georgeJosephg akarMartina schwartzNelson ugwuEmily smithAya liuArya maniSalah chouairiArpita neogiTristanp driscollSaint george hospital university medical centerGetty imagesYale schoolHuman mutationMaen abou zikiNeha bhat