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Editorial Article: Cancer immunotherapies: How single-cell sequencing can aid informed decision-making An insider’s view on leveraging the latest single-cell technologies, including cell sorting and single-cell sequencing, to understand what drives response or resistance in checkpoint therapies 29 Apr 2021 Immune checkpoint blockade (ICB) therapies have revolutionized oncology treatment and become the standard of care in treating malignancies such as solid tumors 1,2. Despite proving more efficient than conventional chemotherapies or targeted therapies, due to their relatively high rate of response (up to 45% in melanoma patients), ICB presents challenges such as treatment resistance and eventual relapse. As cancer treatments evolve, some of the biggest unknowns in the field still are the factors driving the response or resistance to immunotherapy.

United statesMoshe sade feldmanNational institutes of health gene expression omnibusEditorial articleTranslational cancer immunologyMassachusetts general hospitalUnited statesaApplication cellNational institutesGene expression omnibusஒன்றுபட்டது மாநிலங்களில்மோஷ் சதெ ஃபெல்ட்மந்தலையங்கம் கட்டுரைமொழிபெயர்ப்பு புற்றுநோய் நோயெதிர்ப்புமாசசூசெட்ஸ் ஜநரல் மருத்துவமனைதேசிய நிறுவனங்கள்