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Addex Therapeutics Ltd: Addex s Dipraglurant Restores Synaptic Plasticity in Models of Dystonia important 2 1 - Addex Therapeutics (SIX: ADXN and Nasdaq: ADXN), a clinical-stage pharmaceutical company pioneering allosteric modulation-based drug discovery and development, today announced that dipraglurant was able to rescue long-term impairment of synaptic plasticity in two well validated models of dystonia. The data were published in the journal, Neuropharmacology, under the title Rescue of striatal long-term depression by chronic mGlu5 receptor negative allosteric modulation in distinct dystonia models , by a team led by Antonio Pisani, MD, PhD, from the Department of Brain and Behavioral Sciences, University of Pavia, and Mondino Foundation, Pavia, Italy.

United statesAntonio pisaniTim dyerMike sinclairDepartment of brainJanssen pharmaceuticals incMondino foundationSwiss exchangeCompany annual report on formUniversity of paviaBehavioral sciencesDdiscovery biologyAddex therapeuticsJanssen pharmaceuticalsAmerican depositary sharesLooking statements