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Editorial: Subpopulations of AIB1-expressing breast cancer cells enable invasion and metastasis

Editorial: Subpopulations of AIB1-expressing breast cancer cells enable invasion and metastasis
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Amberj kilitiAnnat riegelAnton wellsteinGhadam sharifCancer researchGeorgetown university medical centerAmplified in breast cancer

AIB1-Expressing Breast Cancer Cells Enable Invasion, Metastasis

AIB1-Expressing Breast Cancer Cells Enable Invasion, Metastasis
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Ghadam sharifAmberj kilitiAnnat riegelAnton wellsteinCancer researchGeorgetown university medical centerOncotarget volumeAmplified in breast cancer

Study shows how senescent cells can be an underlying cause of kidney damage

A study in mice by researchers at Georgetown Lombardi Comprehensive Cancer Center has found that stress and tissue damage initiated by angiotensin II, a molecule that is known to increase blood pressure and stiffening in the linings of blood vessels, leads to cellular senescence, a process by which a cell ages and permanently stops dividing but does not die.

Shaunt mehdikhaniMargarida mendenocaWilliam welchBhaskar kallakuryEmily hendersonAnton wellsteinIrfan khanMoshe leviMarcelo schmidtAnnat riegelSidharth jainChristophers wilcoxGeorgetown universityGeorgetown university institutional fundsGeorgetown lombardi comprehensive cancer centerHypertension foundation

Study: Cancer treatment outcomes can be accessed by studying DNA tags

Study: Cancer treatment outcomes can be accessed by studying DNA tags
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United statesAnton wellsteinGeorgetown lombardi comprehensive cancer centerCancer centerGeorgetown lombardiMegan barefootஒன்றுபட்டது மாநிலங்களில்ஜார்ஜ்டவுன் லோம்பார்டி விரிவான புற்றுநோய் மையம்புற்றுநோய் மையம்ஜார்ஜ்டவுன் லோம்பார்டி

Analysis of DNA tags could advance the understanding and treatment of many cancers

Analysis of DNA tags could advance the understanding and treatment of many cancers Cell-free DNA (cfDNA) shed into the blood was discovered in the late 1940s but with rapid advances in genomics and computational analytics in just the past few years, researchers at Georgetown Lombardi Comprehensive Cancer Center now believe that studying tags, or modifications to this type of DNA, may lead to a better understanding of how to assess, and possibly modulate, treatment approaches for cancer and other diseases. Their perspective, drawn from a review of studies to date, appears July 27 in Frontiers in Genetics. During cell death, which is a normal part of tissue regeneration, cfDNA is shed from tissue. The shed cfDNA can be isolated from a blood sample, thus providing a reading of cell death across the body in both normal and cancer cells without the need for taking invasive biopsy samples.

Emily hendersonAnton wellsteinGeorgetown universityGeorgetown lombardi comprehensive cancer centerCancer centerGeorgetown lombardiMegan barefootஎமிலி ஹென்டர்சன்ஜார்ஜ்டவுன் பல்கலைக்கழகம்ஜார்ஜ்டவுன் லோம்பார்டி விரிவான புற்றுநோய் மையம்புற்றுநோய் மையம்ஜார்ஜ்டவுன் லோம்பார்டி