that this was going to be a three-dose vaccine. we knew that because we gave the first-two doses so close together. and when you do that, you don t get long-term, durable protection so it was a matter of time before we were going to accept expect a third immunization in order to give a really important boost in antibody responses, virus neutralizing antibody and durability of protection. so, we knew this was coming. and then, on wednesday, israelis published in new england journal of medicine an important study showing those 60 years of age who only received two doses were going into the hospital at at pretty high rates and lots of breakthrough covid infections. where if they got a third immunization, they they did much better and there was a 20% decline in hospitalizations, tenfold decline in cases. so at a minimum, i would have thought they would have brought that down to 60 years of age. and then, today, the centers for disease control in their mmwr,
saying no to pfizer boosters for everyone else and it s a set back for the white house. doctor, thank you for joining us. appreciate it. yes vote for boosters 65 and up and health care workers and people at risk. why this decision and why not for everyone? well, don, it wasn t quite the decision i was expecting or hoping for. i would have taken an intermediate position between those two. here is why. we ve been talking since the beginning of the year this was going to be a three-dose vaccine. we knew that because we gave the first two doses so close together and when you do that, you don t get long-term durable protection so it was a matter of time before we can expect a third immunization in order to give a really important boost in antibody responses, virus
. yes, i just wanted to ask again if you can provide details for the plan on administering the booster shots. you have to reach the same number of people as the current campaign and many of the federal mask vaccination sites have closed. will we see them shift to doctor s offices? smaller clinics, and will they continue to be an intermediary? and secondly can you tell us, are you focused a lot on the data looking at antibody responses to vaccines, can you tell us what we learned about the t cell response, and the recommendation of boosters next year or the years to come? yeah, first there are 80,000 sites across the country.
a new study has come out ten days ago or so is revealing tha what you and i have been talkin about with others on this program for a long time which i the acquired immunity, the basi immune response after a covid exposure. its durable, it s broad, after persistent antibody responses and memory b and t cells, the results suggest broad and effective immunity may persist long term and recovered covid 1 patients. why has doctor 5 fauci and the cdc director, why do they so vigorously avoid the topic of natural immunity? why? think this goes back to the who when they removed natural immunity from the definition of herd immunity and there was so
Efficacy of mRNA vaccine-induced memory B cells against SARS-CoV-2 variants
Vaccination has been deemed the only effective way to contain the ongoing coronavirus disease 2019 (COVID-19) pandemic, which is caused by the rapid outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Several vaccines have received approval from various regulatory bodies across the world, which has led to widespread vaccination campaigns in these nations.
As vaccines become more readily available to the global population and life begins to return to normal, it is crucial to understand the strength of the protective humoral immunity induced by both natural SARS-CoV-2 infection and COVID-19 vaccines.