As antibiotic resistance continues to pose a formidable challenge, AI-driven solutions offer a beacon of hope in the fight against drug-resistant pathogens. TheHealthSite.com
Naturally occurring and synthetic nanostructured surfaces have been widely reported to resist microbial colonization. The majority of these studies have shown that both bacterial and fungal cells are killed upon contact and subsequent surface adhesion to such surfaces. This occurs because the presence of high-aspect-ratio structures can initiate a self-driven mechanical rupture of microbial cells during the surface adsorption process. While this technology has received a large amount of scientific and medical interest, one important question still remains: what factors drive microbial death on the surface? In this work, the interplay between microbial-surface adhesion, cell elasticity, cell membrane rupture forces, and cell lysis at the microbial-nanostructure biointerface during adsorptive processes was assessed using a combination of live confocal laser scanning microscopy, scanning electron microscopy, in situ amplitude atomic force microscopy, and single-cell force spectroscopy. Sp
Certain copycat eyedrops may be contaminated and could give users an antibiotic-resistant eye infection, the U.S. Food and Drug Administration warned Wednesday.
Swallowing an antibiotic is like carpet-bombing the trillions of microorganisms that live in the gut, killing not just the bad but the good, too, said Dr. Martin Blaser, author of the book "Missing Microbes" and director of the Center for Advanced Biotechnology and Medicine at Rutgers University. Drug-resistant bacteria are already in all of us; beneficial bacteria help keep them controlled. When an antibiotic wipes out beneficial bacteria, the resistant bugs can flourish, making present and future infections harder to treat