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Both Covid jabs are working well in the real world, not just the lab | Vaccines and immunisation

Is 12 weeks between Covid jabs too long?

Is 12 weeks between Covid jabs too long? David Spiegelhalter and Anthony Masters © Provided by The Guardian Photograph: Murdo MacLeod/The Observer The UK has a controversial policy of giving second doses of coronavirus vaccine 12 weeks after the first dose, rather than the three-week gap used in other countries. What is the reasoning behind what the First, since there are limited doses of vaccine, this strategy means protecting more people, faster. This is an optimisation problem against supply constraints, time and a deadly virus. Modelling showed that, provided the first dose delivered reasonable efficacy, then most lives would be saved by lengthening the gap. By 17 February, there had been about 17 million vaccinations in the UK, with more than 16 million people having had a first dose. If a three-week gap had been used, only about 10 million would have had any vaccine.

Is Covid more deadly and contagious than seasonal flu?

Covid-19 and influenza are both respiratory diseases, but there are important differences, which statistics can help us understand. First, Sars-CoV-2 is more infectious than seasonal flu. We’re used to hearing about the reproduction number R, the average number of people whom someone with the virus will infect. In a population without immunity and policies such as social distancing, R for Sars-CoV-2 is now estimated to be around 3. New mutations.

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