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In Singapore, we are looking to double our reporting team by this year-end to comprehensively cover the fast-moving world of funded startups and VC, PE & M&A deals. We want reporters who can tell our readers what is really happening in these sectors and why it matters to markets, companies and consumers. The ability to write precisely and urgently is crucial for these roles. Ideal candidates must have to ability to work in a collaborative, dynamic, and fast-changing environment. We want our new hires to be digi
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Molecular biologist Andrew Holland receives President s Frontier Award
The $250,000 Johns Hopkins award recognizes scholars who are on the cusp of becoming leaders in their fields By Saralyn Cruickshank / Published Feb 15, 2021
Cell division is the fundamental process for life. But when it goes awry, life itself can be threatened.
The fragile balance of centrosomes within animal cells and the cellular functions these organelles control are essential to a form of cell division called mitosis. That s where molecular biologist Andrew Holland focuses his research. We ve been trying to understand if there are differences in the way healthy cells and tumor cells divide, and if we can exploit those differences in therapies to selectively destroy dividing tumor cells and spare the healthy cells, said Holland, an associate professor in the Department of Molecular Biology and Genetics and the Department of Oncology at the Johns Hopkins Schoo
The research in Groopman’s program involves the development and application of molecular biomarkers of exposure, dose and effect from environmental carcinogens, including naturally occurring agents in the diet as well as those produced as a result of cooking practices. A major emphasis of the research has been in the elucidation of the role of aflatoxins, a common contaminant of the food supply, in the induction of liver cancer in high-risk populations living in Asia and Africa. This work has led to the identification of a strong chemical-viral interaction between aflatoxin and the human hepatitis B virus in the induction of liver cancer. These biomarkers have also been used in many collaborative molecular epidemiology studies of liver cancer risk and recently employed to assess the efficacy of a number of chemopreventive agents in trials in high-risk aflatoxin-hepatitis B virus–exposed populations. This research is now being extended to develop genetic biomarkers of p53 mutation
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