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CDK9 Inhibitor SLS009 Displays Activity in Relapsed/Refractory AML

Enrollment of patients in a phase 2 study evaluating SLS009 in relapsed/refractory AML has been completed and the agent demonstrated initial efficacy.

Angelos stergiou

SELLAS Announces Positive Phase 2 Preliminary Data of SLS009 in r/r AML Achieving a 100% Response Rate in Patients with ASXL1 Mutation At the Optimal Dose Level

SELLAS Announces Positive Phase 2 Preliminary Data of SLS009 in r/r AML Achieving a 100% Response Rate in Patients with ASXL1 Mutation At the Optimal Dose Level
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Angelos stergiouBruce mackleJoshua zeidnerLife sciences group incDrug administrationLeukemia researchCompany filed ip protectionWorld health organizationLifesci advisorsDivision of hematologyGenfleet therapeutics shanghai incMemorial sloan kettering cancer centerClinical cancer research commercial integrationPositive phaseResponse rateOptimal dose

SLS009 Plus Venetoclax/Azacitidine Produces Responses in R/R AML, Including ASXL1+ Disease

SLS009 plus venetoclax and azacitidine elicited responses in patients with relapsed/refractory AML, particularly in those harboring ASXL1 mutations.

Angelos stergiouLife sciences groupSciences groupHematologic oncologyAcute myeloid leukemia

SELLAS Life Sciences Announces Positive Recommendation of Independent Data Monitoring Committee Following Completion of Enrollment in REGAL Phase 3 Study

SELLAS Life Sciences Announces Positive Recommendation of Independent Data Monitoring Committee Following Completion of Enrollment in REGAL Phase 3 Study
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Angelos stergiouLife sciences group incMemorial sloan kettering cancer centerData monitoring committeeGenfleet therapeutics shanghai incBruce macklemanaging directorlifesci advisorsStudy steering committeeSafety data assessedIndependent data monitoring committeeRecommends continuationPatients treatmentFollow up without any modificationsConvene again aheadNext efficacySafety assessmentSciences group

SELLAS Life Sciences Announces Positive Recommendation Of Independent Data Monitoring Committee Following Completion Of Enrollment In REGAL Phase 3 St

SELLAS Life Sciences Announces Positive Recommendation Of Independent Data Monitoring Committee Following Completion Of Enrollment In REGAL Phase 3 St
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Bruce mackleAngelos stergiouGenfleet therapeutics shanghai incLifesci advisorsData monitoring committeeMemorial sloan kettering cancer centerStudy steering committeeLife sciences group incSafety data assessedIndependent data monitoring committeeRecommends continuationPatients treatmentFollow up without any modificationsConvene again aheadNext efficacySafety assessment