For 378 days, the foursome physician Nathan Jones, MD, structural engineer Ross Brockwell, microbiologist Ancca Selariu, Ph.D., and biomedical researcher and ultrarunner Kelly Haston, Ph.D. will isolate themselves in a 3D-printed structure called Mars Dune Alpha, which sits inside a large white warehouse at the NASA Johnson Space Center in Houston. Inside the 1,700-square-foot habitat (NASA's word for Mars Dune Alpha), the crew will live and work as if they really are in a spacecraft on Mars.