The Susquehanna River flows from Lake Otsego, New York, to the Chesapeake Bay in Maryland. Near Sunbury, it is joined by the west branch; near Pittston, it is joined by the Lackawanna; north, it forms a triangle at Tioga and is joined by the Chemung. The earliest settlers in the region, known as Wyomink, had been living here for thousands of years, as evidenced by artifacts on display at the Luzerne County Historical Society. For unknown reasons, by 1575, this people disappeared from the area. It is unclear how or why. It wasnât until about the 1650s that the area was populated again. A band of Native Americans from the northeast claimed sovereignty over the area. They were the Iroquois Confederacy, the name given to the confederation or league of five nations: Mohawk, Oneida, Onondaga, Cayga and Seneca. When English settlers began arriving around the 1660s, they decided they wanted this land.