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Deciphering progesterone s mechanisms of action in breast cancer

Deciphering progesterone s mechanisms of action in breast cancer
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Rajendraa badweSudeep guptaMukuls godboleAmit duttSuhail ahmadGaurav chakravortyHomi bhabha national instituteTata memorial centreWorld peace universityPeace university

New research sheds light on role of progesterone in breast cancer

A new research perspective was published in Oncotarget's Volume 14 on July 1, 2023, entitled, "Deciphering the mechanisms of action of progesterone in breast cancer."

Danielle ellisRajendraa badweSuhail ahmadSudeep guptaMukuls godboleAmit duttGaurav chakravortyTata memorial centreWorld peace universityHomi bhabha national institutePeace universityBreast cancer

Precision Oncology Company 4baseCare launches one-of-its-kind Indian Population Specific Cancer Gene Panel

Bangalore (Karnataka) [India], August 18 (ANI/NewsVoir): 4baseCare, a precision oncology company in India, launched their product - TARGT Indiegene, India's largest and first population-specific tumour gene panel derived from Whole Exome and Whole Transcriptome data of over 1,500 cancer patients across 28 different cancer types. Most of the patients were presented with stage III/IV disease, and presented with disease progression and had exhausted all the options in the standard of care.

Hitesh goswamiAmit duttKumar prabhashIllumina accelerator companyActrec tata memorial centreWhole exomeWhole transcriptomeTata memorial centreIllumina acceleratorMount judi venturesSeason two venturesFirst in venturesMedical oncologistPrincipal investigatorஹிடேஷ் கோசுவாமிஅமித் தத்

Study: Lung squamous patients harboring druggable mutations have lower median overall survival

Study: Lung squamous patients harboring druggable mutations have lower median overall survival Oncotarget published Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations which reported that unlike lung adenocarcinoma patients, there is no FDA-approved targeted-therapy likely to benefit lung squamous cell carcinoma patients. The authors performed survival analyses of lung squamous cell carcinoma patients harboring therapeutically relevant alterations identified by whole exome sequencing and mass spectrometry-based validation across 430 lung squamous tumors. They report a mean of 11.6 mutations/Mb with a characteristic smoking signature along with mutations in TP53, CDKN2A, NFE2L2, FAT1, KMT2C, LRP1B, FGFR1, PTEN and PREX2 among lung squamous cell carcinoma patients of Indian descent.

Amit duttKumar prabhashEmily hendersonOncotarget research outputDutt prabhash research teamPrabhash research teamSquamous cell carcinomaExome sequencingLung cancerMass spectrometryஅமித் தத்குமார் பிரபாஷ்எமிலி ஹென்டர்சன்பிரபாஷ் ஆராய்ச்சி அணி

Oncotarget: Lung squamous cell carcinoma tumors reveal therapeutic alterations

Lung cancer is the leading cause of cancer-related deaths across the globe with more than 1.7 million deaths annually.

Amit duttKumar prabhashDutt prabhash research teamPrabhash research teamOncotargetresearch outputScience mathMedicine healthBreast cancerProstate cancerPolicy ethicsஅமித் தத்குமார் பிரபாஷ்ஒலி கிளவுட்பிரபாஷ் ஆராய்ச்சி அணி