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B cells drive responses of other immune cells, can be modified to prevent multiple sclerosis symptoms

Penn Medicine research finds that abnormally active B cell metabolism causes an inflammatory immune response in individuals with MS.

Nathan deveryOr of perelman school medicinePenn centerAmit bar orPerelman schoolScience immunologyPenn medicine

B cells drive responses of other immune cells, and can be modified to prevent Multiple Sclerosis symptoms

B cells can control responses of myeloid cells through the release of particular cytokines (small proteins that control the growth and activity of cells in the immune system), challenging the prevailing view that T cells are the principle orchestrators of immune responses. In individuals with Multiple Sclerosis (MS), abnormally active respiration in B cells drives pro-inflammatory responses of myeloid cells and T cells, leading them to attack the protective sheath (myelin) that covers nerve fibers, and leading to nerve damage that causes symptoms of MS.

United statesUniversity of pennsylvaniaNational institutes of health autoimmunity centerPerelman school of medicineScience foundation of chinaNational naturalPenn centerPaul anderson gift fundPerelman schoolAmit bar orNational institutesHealth autoimmunity centerEpigenomic medicineScience foundation

Altered immune B-cell metabolism drives inflammation in MS: Study

Altered immune B-cell metabolism drives inflammation in MS: Study
multiplesclerosisnewstoday.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from multiplesclerosisnewstoday.com Daily Mail and Mail on Sunday newspapers.

Penn centerUniversity of pennsylvaniaAmit bar or

Researchers find B cells drive responses of other immune cells, can be modified to prevent multiple sclerosis symptoms

Researchers find B cells drive responses of other immune cells, can be modified to prevent multiple sclerosis symptoms
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Rui liPerelman school of medicinePenn centerUniversity of pennsylvaniaScience immunologyPerelman schoolAmit bar or

B Cells Drive Responses Of Other Immune Cells

B Cells Drive Responses Of Other Immune Cells
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

United statesUniversity of pennsylvaniaNational institutes of health autoimmunity centerPerelman school of medicinePaul anderson gift fundPenn centerScience foundation of chinaNational naturalMultiple sclerosisPerelman schoolAmit bar orNational institutesHealth autoimmunity centerEpigenomic medicineScience foundation