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Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

News-Medical speaks to Dr. Cicely Fadel and Amir Bein about their latest research which involved the development of an Environmental Enteric Dysfunction (EED) Chip that reveals the effects of nutrition and genetics on disease in children

Israel generalAgha khanUnited statesMarko aliaksandr shutterstockDanielle ellisCicelyw fadelCicely fadelChild health discovery toolsBeth israel deaconess medical centerMelinda gates foundationPerinatal fellowship programHebrew university of jerusalemEquality divisionInstructor in pediatrics at harvard medical schoolResponsibility programYale university

Novel Intestine Chip Provides Insights Into Environmental Enteric Dysfunction

Researchers have created an

United statesNat biomed engCicely fadelDonald ingberNeonatologist at beth israel deaconess medical centerSenior postdoctoral researchAga khan universityWyss instituteWyss institute foundingWyss institute intestine chipsInstructor in pediatrics at harvard medical schoolWyss institute at harvard universityGates foundationHarvard universityIntestine chipIntestine chips

Novel Intestine Chip Provides Insights Into Environmental Enteric Dysfunction

Researchers have created an <i>in vitro</i> human model of environmental enteric dysfunction in a microengineered Intestine Chip device, providing a window into the complex interplay between malnutrition and genetic factors driving the disease.

United statesNat biomed engCicely fadelDonald ingberNeonatologist at beth israel deaconess medical centerSenior postdoctoral researchAga khan universityWyss instituteWyss institute foundingWyss institute intestine chipsInstructor in pediatrics at harvard medical schoolWyss institute at harvard universityGates foundationHarvard universityIntestine chipIntestine chips

Modeling devastating childhood disease on chip

Modeling devastating childhood disease on chip
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United statesUniversity of cincinnatiRachelle prantil baunJennifer grantBen swenorSanjay sharmaCicely fadelAndrew parsonsAsad aliArash naziripourWuji caoGirija goyalSeongmin kimJunaid iqbalLee densonDavid breault

Tackling Life s Toughest AI Challenge

Quris describes how a new AI approach can improve predictions of which drug candidates will work safely in the human body.

United statesRoberts langerIsaac bentwichAaaron ciechanoverEuropean parliamentMassachusetts institute of technologyInstitute professorAmir beinVice presidentVan normanMassachusetts instituteIsomorphic laboratoriesInsilico medicineClinical prediction

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