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CAR-T Therapy: Combating Cytokine Release Syndrome

CAR-T Therapy: Combating Cytokine Release Syndrome Sponsored Content by ACROBiosystemsMay 21 2021 CAR-T cell therapy offers the hope of a cure to a number of cancer patients. Yet, in spite of the great effectiveness, more attention has been paid to the toxicity of the therapy known as cytokine release syndrome (CRS). This article is aimed at summarizing the main points of assessment, grading and management of CRS in CAR-T Therapy and provide answers to the following questions: How to identify the onset of CRS clinically? What is CRS management? How to use tocilizumab in CRS management? Assessment, grading and management of CRS in CAR-T therapy

Tocilizumab plus standard care versus standard care in patients in India with moderate to severe COVID-19-associated cytokine release syndrome (COVINTOC): an open-label, multicentre, randomised, controlled, phase 3 trial

Tocilizumab plus standard care versus standard care in patients in India with moderate to severe COVID-19-associated cytokine release syndrome (COVINTOC): an open-label, multicentre, randomised, controlled, phase 3 trial
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The Impact of COVID-19 on Oncology Pharmacy and Patient Care, Part 1

Angiocrine Bioscience Announces Oral Presentation of Intravenous AB-205 Data during the Annual Transplantation & Cellular Therapy Meetings of ASCT and CIBMTR

Share this article Share this article SAN DIEGO, Feb. 5, 2021 /PRNewswire/ Angiocrine Bioscience Inc., a clinical-stage biopharmaceutical company today announced that the American Society for Transplantation and Cellular Therapy (ASTCT) and the Center for International Blood & Marrow Transplant Research (CIBMTR) has selected Angiocrine s AB-205 Phase 1b/2 study results for an oral presentation. Intravenous AB-205 is being developed to treat diffuse damage of vascular niches of multiple organs caused by off-target cytotoxicity from high-dose chemotherapy (HDT) in the course of conditioning patients undergoing autologous hematopoietic cell transplantation to effect a cure of aggressive lymphomas. Treating the damaged vascular niches enable prompt repair of multiple organs. In case of HDT, the most severely and frequently affected organ systems are oral-gastrointestinal and hematopoietic. By enabling multi-organ repair, AB-205 has the potential of substantially reducing the inci

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