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Heart disease, depression linked in inflammation study

Fight or flight response may hinge on protein in skeletal muscular system

 E-Mail Credit: Colleen Kelley/University of Cincinnati Researchers at the University of Cincinnati say a regulatory protein found in skeletal muscle fiber may play an important role in the body s fight or flight response when encountering stressful situations. The protein, fast skeletal myosin binding protein-C (fMyBP-C), plays a foundational role in the proper regulation of contractile structure and function in the body s fast twitch muscles these muscles produce sudden bursts of power to sprint into action, jump or lift heavy objects. Fast skeletal myosin binding protein-C modulates the speed and force of fast skeletal muscle contraction. This response is very critical for the higher animal and human survival. Just imagine, you are walking through a forest and suddenly you see a tiger in front of you, says Sakthivel Sadayappan, PhD, a professor in the UC Division of Cardiovascular Health and Disease. You will immediately act, either to fight or run away from the animal.

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