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Operator: Good day and thank you for standing by. Welcome to the Rhythm Pharmaceuticals Fourth Quarter and Full Year 2022 Earnings Conference Call.

United statesUnited kingdomDave connollyYann mazabraudPiet wigerinckJennifer chienDavid meekerPhilip nadeauHunter smithDavid connollyAmerica team meetingInternational patient organizationGeneration battery technology companiesHead of internationalRhythm pharmaceuticalsRhythm pharmaceuticals inc