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LEQEMBI® (lecanemab-irmb) NAMED ONE OF TIME s BEST INVENTIONS OF 2023

Recognized in the Medical Care Category NUTLEY, N.J., and CAMBRIDGE, Mass., Oct. 24, 2023 /PRNewswire/  Eisai Inc. and Biogen Inc. are honored to announce today that TIME has selected LEQEMBI® .

Axsome Therapeutics Presents Results of the ACCORD trial of AXS-05 in Alzheimer s Disease | Region

NEW YORK, Oct. 24, 2023 (GLOBE NEWSWIRE) Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company developing and delivering novel therapies for the management of central nervous system (CNS) disorders,

Orexin: The New Kid on the Insomnia Block

Dementia Linked to Financial and Care Strain

People with dementia are associated with needing more help with daily activities, having financial burdens, and having more hospital and nursing facility stays, according to new data.

Large-scale plasma proteomics comparisons through genetics and disease associations

High-throughput proteomics platforms measuring thousands of proteins in plasma combined with genomic and phenotypic information have the power to bridge the gap between the genome and diseases. Here we performed association studies of Olink Explore 3072 data generated by the UK Biobank Pharma Proteomics Project1 on plasma samples from more than 50,000 UK Biobank participants with phenotypic and genotypic data, stratifying on British or Irish, African and South Asian ancestries. We compared the results with those of a SomaScan v4 study on plasma from 36,000 Icelandic people2, for 1,514 of whom Olink data were also available. We found modest correlation between the two platforms. Although cis protein quantitative trait loci were detected for a similar absolute number of assays on the two platforms (2,101 on Olink versus 2,120 on SomaScan), the proportion of assays with such supporting evidence for assay performance was higher on the Olink platform (72% versus 43%). A considerable number

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