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The findings of a randomized, placebo-controlled trial of 963 patients throw into doubt the use of vitamin C for people with sepsis. In organ dysfunction, the treatment did worse than placebo.

New zealandNeill adikhariFrancois lamontagneAlphaa fowlerUniversity of torontoUniversity of sherbrookeVirginia commonwealth universityNew england journalSequential organ failure assessmentBloodstream infectionsSeptic shockAcute respiratory distress syndromeCute respiratory distress syndrome ardsAdult respiratory distress syndromeNoncardiogenic pulmonary edemaOncardiogenic pulmonary congestion