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Carryover is an all-too-common problem for many users of High Performance Liquid Chromatography (HPLC) systems. There are multiple forms of carryover, including volumetric, or carryover as a result of void volumes in the flow path, and adsorptive carryover, where sample “sticks” or adsorbs to surfaces of the flow path. If a method suffers from carryover, it is important to know which form of carryover it is so that you can most effectively eliminate the source of the carryover. In many cases,
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