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NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines

NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines A clinical trial is underway to determine whether people who are highly allergic or have a mast cell disorder are at increased risk for an immediate, systemic allergic reaction to the Moderna or Pfizer-BioNTech COVID-19 vaccines. A systemic allergic reaction to a vaccine occurs in one or more parts of the body beyond the injection site. If such an allergic reaction occurs in study participants, investigators will assess whether the reactions are more frequent in participants who are highly allergic or have a mast cell disorder than in participants with no allergic history. In addition, investigators will examine the biological mechanism behind the reactions and whether a genetic pattern or other factors can predict who is at most risk.

NIH begins study of allergic reactions to Moderna, Pfizer-BioNTech COVID-19 vaccines

Adults interested in participating in this trial should visit ClinicalTrials.gov and search under study identifier   for study locations and contacts. Please do not use the NIAID media phone number or email address to try to enroll in this trial.   Colorized scanning electron micrograph of a cell (orange) infected with UK B.1.1.7 variant SARS-CoV-2 virus particles (green), isolated from a patient sample.NIAID A clinical trial is underway to determine whether people who are highly allergic or have a mast cell disorder are at increased risk for an immediate, systemic allergic reaction to the Moderna or Pfizer-BioNTech COVID-19 vaccines. A systemic allergic reaction to a vaccine occurs in one or more parts of the body beyond the injection site. If such an allergic reaction occurs in study participants, investigators will assess whether the reactions are more frequent in participants who are highly allergic or have a mast cell disorder than in participants with no allergic history.

NIH begins study of allergic reactions to Moderna, Pfizer-BioNTech COVID-19 vaccines

NIH begins study of allergic reactions to Moderna, Pfizer-BioNTech COVID-19 vaccines
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NIH begins study of allergic reactions to Moderna, Pfizer-BioNTech COVID-19 vaccines

NIH begins study of allergic reactions to Moderna, Pfizer-BioNTech COVID-19 vaccines
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Relief for people with chronic sinusitis and nasal polyps

Relief for people with chronic sinusitis and nasal polyps Published:  Tags:  FORT LAUDERDALE, Fla. – Shara Sexton is among the 29 million people in the U.S. suffering from chronic sinusitis and the problem was compounded by nasal polyps. “Breathing through my mouth and not being able to breathe through my nose; if you would close my mouth I felt like I would suffocate,” she said. “Virtually all patients with nasal polyps have chronic sinusitis because they physically obstruct the drainage patterns of the sinuses and don’t allow them to function normally,” said Otolaryngologist Dr. Richard Callari with Broward Sinus and Allergy Center.

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