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Metabolic dysfunction-associated steatohepatitis, or MASH, is an inflammatory, liver-scarring disease that has reached epidemic proportions, with an estimated 1.5% to 6.5% of U.S. adults afflicted by the condition, and roughly 24% of adults having nonalcoholic fatty liver disease (NAFLD). MASH, previously known as nonalcoholic steatohepatitis or NASH, is a more serious complication of NAFLD, now called metabolic dysfunction-associated steatotic liver disease or MASLD. The nomenclature(op.