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Biogen and Innocare Announce License and Collaboration

Biogen and Innocare Announce License and Collaboration Agreement For Orelabrutinib, an Innovative CNS Penetrant BTK Inhibitor For the Potential Treatment of Multiple Sclerosis Biogen Inc.; InnoCare Pharma Limited Cambridge, Massachusetts, UNITED STATES Orelabrutinib is a Phase 2 oral small molecule Bruton’s tyrosine kinase inhibitor with high selectivity and the ability to cross the blood-brain barrier InnoCare to receive a $125 million upfront payment and is eligible to receive potential development and commercial milestone payments CAMBRIDGE, Mass. and BEIJING, July 12, 2021 (GLOBE NEWSWIRE) Biogen Inc. (Nasdaq: BIIB) and InnoCare Pharma Limited (HKEX: 09969) today announced that they have entered into a license and collaboration agreement for orelabrutinib, an oral small molecule Bruton’s tyrosine kinase inhibitor (BTKi) for the potential treatment of multiple sclerosis (MS). Orelabrutinib is a covalent BTKi with high selectivity and the abil

Biogen pays InnoCare $125m upfront for potential multiple sclerosis treatment

Biogen pays InnoCare $125m upfront for potential multiple sclerosis treatment
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FDA trims use of contentious Alzheimer s drug amid backlash

FDA trims use of contentious Alzheimer s drug amid backlash AP FILE - This image provided by Biogen on Monday, June 7, 2021 shows a vial and packaging for the drug Aduhelm. On Thursday, July 8, 2021, U.S. health regulators approved new prescribing instructions for the controversial Alzheimer s drug that are likely to limit use of the expensive therapy, which has faced an intense public backlash. (Biogen via AP, File) By: The Associated Press & Scripps National Posted at 11:48 AM, Jul 08, 2021 and last updated 2021-07-08 14:48:51-04 WASHINGTON (AP) — The Food and Drug Administration (FDA) has approved new prescribing instructions that are likely to limit the use of a controversial new Alzheimer s drug.

FDA narrows prescribing information for Alzheimer s disease drug

AP Steven Senne/AP The US Food and Drug Administration has narrowed the group of Alzheimer s disease patients who should receive the controversial drug aducanumab By Jacqueline Howard, CNN The US Food and Drug Administration has narrowed the group of Alzheimer’s disease patients who should receive the controversial drug aducanumab, sold as Aduhelm. The FDA approved changing the drug’s label to clarify that the treatment is intended specifically for patients with mild cognitive impairment or milder stages of disease, according to an announcement Thursday from the companies Biogen and Eisai. “Treatment with Aduhelm should be initiated in patients with mild cognitive impairment or mild dementia stage of disease, the population in which treatment was initiated in clinical trials. There are no safety or effectiveness data on initiating treatment at earlier or later stages of the disease than were studied,” the new prescribing information states.

FDA narrows label for Biogen s Aduhelm to only include mild forms of Alzheimer s disease

FDA narrows label for Biogen s Aduhelm to only include mild forms of Alzheimer s disease
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