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Can mRNA vaccines cure cancer?

mRNA technology transforms the human body into a virus-zapping vaccine factory, teaching cells how to make a protein that triggers an immune response against viruses

South africaUnited statesUnited kingdomAlexander bukreyevOzlem tureciScott hensleyNorbert pardiZabdeno mvabeaHarvey friedmanEdward jennerUgur sahinUniversity of pennsylvaniaWorld health organisationVaccine initiativeHuman immunodeficiencyBrett leav

LJI Scientists Discover Clue to Stopping Lassa Virus Infection

In a new study, researchers show how a critical Lassa virus protein, called polymerase, drives infection by harnessing a cellular protein in human hosts. Their

Erica ollmann saphireAlexander bukreyevGogce crynenHaydar witwitKelvin frank choAlicey tingGeorge tsaprailisJingru fangDeliab baxter foundationNational institutes of healthResearch associate colette pietzschUniversity of texas medical branchJolla instituteScripps researchProceedings of the national academy sciencesJolla institute for immunology

Study shows how a critical Lassa virus protein drives infection

Lassa fever is a viral illness that is far too common in West Africa. Although it can have a mortality rate of 15 percent in severe cases, up to 90% in pregnant women, and causes deafness in a quarter of survivors, there is no vaccine or antiviral to protect against Lassa virus.

Erica ollmann saphireAlexander bukreyevJingru fangEmily hendersonScripps researchProceedings of the national academy sciencesJolla institute for immunologyScripps research professor juan de la torreResearch associate colette pietzschUniversity of texas medical branchNational academyOllmann saphireProfessor alexander bukreyevTexas medical branchCell reports

Scientists identify a promising strategy for stopping Ebola virus polymerase

To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase.

Erica ollmann saphireAlexander bukreyevJingru fangEmily hendersonScripps researchStanford university professor alice tingJolla institute for immunologyUniversity of texas medical branchOllmann saphireCell reportsTexas medical branchProfessor alexander bukreyevCell lineEbola virus diseaseHepatitis cImmune system

Promising antibody cocktail takes on Ebola virus-and its deadly cousin

Promising antibody cocktail takes on Ebola virus-and its deadly cousin
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Erica ollmann saphireAlexander bukreyevIan crozierXiaoying yuRobertw crossCarl davisSean huiCarlw davisKai huangPeter halfmannViktoriya borisevichJacobc milliganPhilippa ilinykhArthurj goffJensh kuhnLuism branco