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Aug. 3, 2021 , 4:49 PM If there’s one defining trait of daddy longlegs, it has to be their legs. Now, scientists have shortened the legs of one species and turned them into food-handling limbs by tweaking the arachnids’ DNA expression. To figure out which genes cause these spider relatives to develop long legs, researchers assembled the first draft genome of Phalangium opilio and looked at three genes that act as a blueprint for where various body parts should go. When they traced the activity of two of those genes, they found they were turned on in the legs of embryos under a microscope. Next, they used RNA interference a technique that reduces gene expression to knock them down in hundreds of developing

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