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In HIV, gene therapy could be alternative path to functional cure

At the 30th Annual Congress of the European Society for Gene and Cell Therapy in Brussels this week, researchers presented both preclinical and clinical strategies for applying gene therapy to a functional HIV cure. At a Wednesday session on Infectious Diseases & Vaccines, Alessio Nahmad, of Tabby Therapeutics Ltd., described using B cells edited to express broadly neutralizing antibodies (bnAbs) 3BNC117 to deliver high titers of antibodies in mice.

Bruxelles capitaleAlessio nahmadEuropean society for geneTabby therapeutics ltdAnnual congressEuropean societyCell therapyInfectious diseasesEsgct 2023Hiv reservoirB cellsEbt 101Tabby therapeutics ltdExcision biotherapeutics incHiv cure

Study identifies risks in the use of CRISPR therapeutics

The researchers caution: "The CRISPR genome editing method is very effective, but not always safe. Sometimes cleaved chromosomes do not recover and genomic stability is compromised - which in the long run might promote cancer."

University of pennsylvaniaUnited statesAlessio nahmadAdi barzelAsaf madiElla goldschmidtEmily hendersonEli reuveniEdmondj safra centerWise faculty of life sciencesTel aviv sourasky medical center ichilovSchool of neurobiologyTel aviv universityDotan centerLife sciencesAdvanced therapies

CRISPR Therapeutics Can Damage the Genome, Israeli Researchers Say | The Jewish Press - JewishPress com | Hana Levi Julian | 26 Tammuz 5782 – July 24, 2022

CRISPR Therapeutics Can Damage the Genome, Israeli Researchers Say | The Jewish Press - JewishPress com | Hana Levi Julian | 26 Tammuz 5782 – July 24, 2022
jewishpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from jewishpress.com Daily Mail and Mail on Sunday newspapers.

University of pennsylvaniaUnited statesTom winklerAlessio nahmadAdi barzelBen davidAsaf madiElla goldschmidtEli reuveniEdmondj safra centerWise faculty of life sciencesTel aviv sourasky medical center ichilovSchool of neurobiologyTel aviv universityDotan centerPhoto credit

CRISPR gene editing may cause permanent damage - study

Caution from researchers at Tel Aviv University: CRISPR gene editing can damage the genome and might trigger cancer.

University of pennsylvaniaUnited statesAlessio nahmadEmmanuelle charpentierAdi barzelAsaf madiJennifera doudnaElla goldschmidtEli reuveniSafra centerWise faculty of life sciencesTel aviv sourasky medical centerScientists at tel aviv universitySchool of neurobiologyDotan centerTel aviv university

Israeli Study Says DNA Editing Method Can Damage Genome

CRISPR therapeutics is used for treating cancer, liver and intestinal diseases as well as genetic syndromes - Click the link for more details.

Alessio nahmadAdi barzelEli reuveniTel aviv universityUri ben david

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