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By Susan Gonzalez July 15, 2021 Share this with FacebookShare this with TwitterShare this with LinkedInShare this with EmailPrint this (© stock.adobe.com) The administration of high-dose buprenorphine therapy in hospital emergency departments (ED) may safely and rapidly diminish withdrawal symptoms and sustain craving suppression in people with opioid use disorder, improving their likelihood of accessing follow-up treatment, according to a study co-authored by Yale’s Gail D’Onofrio. Buprenorphine is a medication approved by the U.S. Food and Drug Administration to treat opioid use disorder. Giving lower doses of the medication is the current standard of care. The study found, however, that giving higher doses of buprenorphine in EDs may provide a longer period of relief to people after they are discharged, which may help them navigate barriers to access to follow-up care before they experience withdrawal symptoms.

United statesDavid fiellinNorad volkowAlberte kentYale gail donofrioYale program in addiction medicineNational institute on drug abuseAlameda health systemYale school of medicineClinical trials networkNational institutes of healthUs department of healthHuman servicesDrug administrationDepartment of emergency medicineInitiative on opioids