Supporting Information) under laser irradiation and resulted in PTT of the cancer cells (Figures 5, 6, and 8E). Secondly, the photothermally generated microbubbles enhanced acoustic cavitation (Figures 4 and 6D), their mechanical effects are able to destroy adjacent cancer cells and cause cell death (Figures 6A and 8E). Thus, the combination of PTT and cavitation-mediated cell destruction significantly improved the therapeutic outcomes as compared to the PTT alone (Figures 5, 6 and 8).
Conclusion
A “one-for-all” theranostic [email protected] nanodroplet with low-boiling PFP as the core and PPy that exhibited broad optical absorption constituting the shell was successfully constructed. The [email protected] nanodroplets represent an efficient PTT agent with outstanding photothermal conversion properties that can efficiently transfer NIR light into local hyperthermia for photothermal ablation of tumors. Meanwhile, the liquid-gas phase transition of the PFP cores was also trigge