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© Chemical & Engineering News Light can switch this azobenzene-modified version of the circadian clock regulator longdaysin between its active and inactive forms, allowing researchers to controllably shift cells’ circadian clocks by up to 4 h. Most living things contain a circadian clock a signaling system that keeps the cell s function tied to the periodicity of a 24-h cycle. Although scientists have identified many elements that regulate the clock s function, much about circadian rhythms and how they influence health and disease remains poorly understood. Now, researchers have created a light-activated molecule that can reversibly shift the length of the clock s cycle in living cells and tissues. The tool provides a targeted, non-invasive way to study how the clock affects cellular physiology, says Ben Feringa, a chemist at the University of Groningen who co-led the work.

Akhilesh reddyDirk traunerBen feringaTsuyoshi hirota at nagoya universityUniversity of pennsylvaniaYork universityUniversity of groningenTsuyoshi hirotaNagoya universityNew york universityபல்கலைக்கழகம் ஆஃப் பென்சில்வேனியாயார்க் பல்கலைக்கழகம்பல்கலைக்கழகம் ஆஃப் க்ராநிகந்நாகோயா பல்கலைக்கழகம்புதியது யார்க் பல்கலைக்கழகம்