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A New Target for Malaria Vaccines
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WASHINGTON, Jan. 7, 2021 /PRNewswire/ An article published in
Experimental Biology and Medicine (Volume 246, Issue 1, January, 2021, https://journals.sagepub.com/doi/pdf/10.1177/1535370220961764) describes a new target for the development therapies and vaccines for malaria. The study from the West African Centre for Cell Biology of infectious Pathogens at the University of Ghana in Accra (Ghana) reports that peptide antibodies against a new merozoite protein (PF3D7 1459400) block parasite entry into red blood cells.
Malaria is a major global health problem with 2.5 billion people at risk of the disease and death. Global elimination of malaria requires an effective vaccine. Despite the huge public health burden of the disease, limited numbers of vaccine candidates are currently under development, and the most advanced candidates display modest efficacy. The development of an effective malaria vaccine has bee