Purpose: The deposition of hydroxyapatite (HAp) crystals plays an important role in the development of vascular calcification (VC). This study aimed to demonstrate the effects of nanosized HAp (nHAp) on vascular smooth muscle cells (VSMCs) and VC progression.
Methods: Transmission electron microscopy (TEM) was used to examine cellular uptake of nHAp. Cell viability was determined using CCK-8 assay kit. Mitochondrial impairment and reactive oxygen species were detected by TEM and fluorescence dye staining, respectively. Cell apoptosis was detected by Western blot analysis and Annexin V staining. Mouse model of VC was built via applying nHAp on the surface of abdominal aorta. Calcification was visualized by Alizarin red and von Kossa staining.
Open Banking platform Tarabut Gateway raises USD 13 mln Tuesday 23 February 2021 14:19 CET | News
Bahrain-headquartered Open Banking platform Tarabut Gateway has raised USD 13 million in a seed round led by Germany-headquartered European VC Target Global.
The round was also joined by UK`s Kingsway and Entrée Capital as well as regional investors like CE Ventures, Zamil Investment Group, Global Ventures, Almoayed Technologies, and Mad’a Investment.
Tarabut Gateway is building services for the Middle East & North Africa, enabling fintechs and other financial services providers to access financial data of the customers from partner banks through its Open Banking APIs, which allows them to build new apps and services. It claims to be the first regulated (and largest) Open Banking platform in the region.
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