Pre-formed fibrils (PFFs) are a cost-effective and novel method for the modeling of neurodegenerative diseases. This article discusses their manufacture, various benefits and the new perspectives they can provide to disease models.
Novel antibody, TB006, demonstrated improvements in cognition and function and was well tolerated in a one-month Phase 1b/2 trial in mild to severe Alzheimer's disease (AD) patientsTB006 also demonstrated
TrueBinding Highlights the Potential of TB006’s Unique Mechanism of Action as a Novel Approach for the Treatment of Alzheimer’s Disease at the 15th Clinical Trials on Alzheimer’s Disease (CTAD) Conference GlobeNewswire December 06, 2022 Novel antibody, TB006, demonstrated improvements in cognition and function and was well tolerated in a one-month Phase 1b/2.
A molecular fluorescence sensor has revealed an abnormal distribution of lipid in the brains of patients with Huntington's disease, enabling researchers to identify a potential cause of brain dysfunction in the disease.