With abortion banned or greatly restricted in many states, dermatologists who prescribe isotretinoin and methotrexate said they are anxious about the future.
An increase in cases began as early as 2014 and intensified during the pandemic. Sales of drugs to treat scabies have increased, but the efficacy of treatments such as permethrin may have declined.
The recommendations, the authors said, "provide a framework for management of a typical, otherwise healthy patient being treated with isotretinoin for acne."