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Combination of dasatinib and blinatumomab offers effective treatment for older Ph+ ALL patients

Older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who were not good candidates for the standard treatment of intensive chemotherapy had a median overall survival (OS) of 6.5 years on an alternate regimen of dasatinib and blinatumomab.

United statesBrentl woodSusanm obrienAnjalis advaniAaront gerdsJeraldp radichMark litzowJanel liesveldMatthew wieduwiltAnna moseleyHarryp erbaLos angelesDeepa jeyakumarGeorge yaghmourCeciliacs yeungKristen odwyer

Studies Highlight Impacts of Applying New Technologies in Everyday Care

/PRNewswire/ Researchers report striking progress in the application of cutting-edge tools and treatments to address longstanding challenges in blood.

United statesCleveland clinicUniversity of hong kongHong kong generalHong kongUnited kingdomDiego marinaAndrew srisuwananukornHarinder gillOliver shastriAaront gerdsIcahn school of medicine at mount sinaiBavarian cancer research instituteTechnology commissionAmerican society of hematologyFriedrich alexander university of erlangen

Combo Treatment Sans Chemotherapy Effective for Ph+ ALL Elderly

Combo Treatment Sans Chemotherapy Effective for Ph+ ALL Elderly
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United statesMark litzowMatthew wieduwiltCeciliacs yeungEhabl atallahAnna moseleySusanm obrienAaront gerdsMegan othusJanel liesveldBrentl woodHarryp erbaAnjalis advaniKristen odwyerElad sharonJeraldp radich

Momelotinib Could Represent Pivotal New Treatment Option in Myelofibrosis

Aaron T. Gerds, MD, PhD, expands on the potential role of momelotinib in the treatment of patients with myelofibrosis who present with anemia, details the data from MOMENTUM, and explains what FDA approval of momelotinib could mean for the treatment of this patient population.

United statesAaront gerdsDevelopmental therapeutics programCleveland clinic taussig cancer instituteDepartment of hematologyDepartment of medicineCase comprehensive cancer centerMedical oncologyCleveland clinic taussig cancerRed crossMyeloproliferative neoplasmCleveland clinic

New Frontiers in the Targeted Treatment of Myelofibrosis

New Frontiers in the Targeted Treatment of Myelofibrosis
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United statesWake forest universityNorth carolinaWinston salemRuben mesaGeron incyteAaront gerdsLevine cancer institute enterprise service lineCleveland clinic taussig cancer instituteWake forest university school of medicineBristol myers squibbAccreditation council for continuing medical educationCase comprehensive cancer centerAtrium healthIntegrity continuing education incClinical research