Headquarters in new york this is nbc nightly news. Reporting tonight, peter alexander. Good evening. His controversial comments about undocumented immigrants from mexico reignited a debate over immigration. Donald trump is taking his blunt talk to the border ground of arizona, the epicenter of this divisive issue. He turned provocative politician ignored pleas to tone down his language. Trump insists he has launched a national movement. We begin in phoenix tonight with nbcs katy tur. Katy . Reporter peter, sit a tense atmosphere out here. Protesters are screaming, chanting. Trump is speaking to his biggest crowd yet. Estimates put it at 5,000 people. We will win usa usa reporter on the streets of phoenix, the mercury matched the rhetoric. 105 degrees and angry. A hot topic with hot opinions. What do you think about his comments on latinos in. He talk the truth. He didnt even say anything wrong. And im surprised very much that people are upset with him because he tells the truth. This guys an idiot. He is trying to divide people instead of uniting the people. Reporter inside a crowd of thousands here to see what donald trump, the president ial candidate has to offer. This is absolutely unbelievable. Thank you, everybody. Reporter here since 4 45 this morning, this woman wanted to be the first in line. Why are you such a strong supporter . Hes a man that says what he says and he doesnt back down. Reporter it was originally scheduled for arizona biltmore. They had to move to a bigger venue, the Phoenix Convention center so more could attend. Is this good for the republican party, senator . I think mr. Trump, when he comes to arizona, will find we arizonans cherish our hispanic influence and heritage. We are going to make this country so great again. Trumps first trip to the border state as a candidate and since defining its Campaign Around immigration. Im the one that burned up the whole situation and the whole mess with immigration and what the Mexican Government is doing for us. Reporter arizona the hotbed in the immigration debate since 2010, when former governor jan brewer signed sb1070, giving the right to police to stop anyone they think might be undocumented. Protesters went head to head with supporters. We are here to tell you to go home. We dont need your racist comments. All youre trying to do is get pub listly. Reporter the twoday blitz began in l. A. With the billionaire and those who lost loved ones at the hands of undocumented immigrants. Peter, this isnt the biggest crowd of the season so far, but it is certainly trumps biggest. He is message is resonating despite or perhaps in spite of the bad press. Back to you. Katy tur on the ground for news arizona tonight. Katy thank you. Chuck todd will have much more on immigration and the trump factor right here tomorrow morning on meet the press. Overseas now. A massive car bomb attack on a western Diplomatic Mission in cairo is raising new questions whether isis is expanding its deadly campaign. The violence is being followed closely here in the u. S. And we get more tonight from Nbcs Kristen Welker at the white house. Reporter egyptian officials surveyed the devastation in cairo where isis has claimed responsibility for this car bomb attack right in front of the italian consulate. One person died many more wounded. Today afghan officials claim a u. S. Drone strike killed a top isis leader in afghanistan. U. S. Military officials cant confirm that. Some doubt its true. But the pentagon admits that drone strikes in eastern afghanistan killed dozens of suspected isis and taliban militants earlier this week. This is like dealing with cancer. Youre not lookingings for a onetime cure. Youre looking to contain the symptoms. Reporter that threat may, in fact be growing. While the air campaign against isis has focused on targets in iraq and syria, u. S. Officials say the past few months local versions have sprouted occupy in yemen, afghanistan. There is a distinction between on the ground force that isis has in syria and iraq versus aspirational force that exists right now in places like afghanistan and pakistan. Reporter this week president obama urged International Response to isis. In recent weeks we have seen deadly attacks in tunisia, kuwait and egypts sinai peninsula. I called to unite against this scourge of extremism. Reporter while isis is claiming territory in iraq and syria, outside the region its a localized threat. Victory is a wrong word to use against isis. We need to contain and mitigate their threat. Reporter military experts insist the best strategy to defeat isis is going after the socalled main body of the group, which is in iraq and syria. Another goal building up partnerships in many of these regions. And thats a challenge because much of the territory is deeply fractured. Peter . Kristen welker thanks. In vienna with the latest deadline on monday the u. S. Iran and other world powers worked into the night to finalize a deal on limiting Irans Nuclear power. More from Andrea Mitchell chief Foreign Affairs correspondent. Reporter late into the night, now for the third weekend in a row, talks got serious. After missing another deadline friday todays secretary kerry and western allies arrived early and stayed late. The negotiations had the feel of musical chairs. Kerry with the german french and british ministers. Then kerry, the european representative and irans foreign minister zarif. Posing with stacks of paper. A draft of the nuclear agreement. Almost done but not there yet. Kerry last night. I think we have resolved some of the things that were outstanding and we made some progress. Reporter after meeting with zarif today, kerry tweeted, still have difficult issues to resolve. One of the last stumbling blocks irans demand backed by russia to lift a u. N. Ban on buying and selling conventional weapons, including ballistic missiles. Both sides accused the other of bad faith. Both are being secondguessed by critics back home. As zarif took a break on his balance cane in tehran, the Ayatollah Khomeini said u. S. s perfect instance of arrogance. Prepare yourself for a fight against arrogance. Most saw that as a chance to placate hard liners. As the world press waited the agreement has been delayed so long a Bridal Company who booked their couple for today in period costume, no less were the only distraction, depart anything a preworld war ii bus. As the negotiators kept at it in overtime. This is the first time the ministers have worked this late since they have been in vienna. A sign of just how hard theyre trying and how tough it is. In fact, this is john kerrys longest trip as secretary and his longest negotiation by far. And hes now approaching the record set by some of his legendary predecessors. Peter . The latest deadline set for monday. Andrea thank you. Hundreds of thousands of people turned out to see and hear pope francis in paraguay the last stop on his south america tour. Throughout the trip the pope delivered a powerful message pushing for economic equality. Our report tonight from nbcs anne thompson. Reporter for latin americas first pope its been an emotional homecoming. Sworn by children in paraguay reaching out to prisoners inside bolivias most notorious prison showered with flower petals in ecuador. Pope francis drawing the worlds attention to three country it rarely sees. He speaks our language like us. Reporter criticizing what he called an intolerable system that seeks profit at any price. A message he is going to bring to the u. S. In september. It will challenge us to think that the Economic System is perfect and that hes going to come and tell us no it isnt. That a lot of people are suffering reporter he wore every symbol of welcome. There was no hat he refused. Today he met with community leaders, including a gay activist. And events featured latin americas native people to whom he begged forgiveness for the crimes committed by the church in settling this region. For so many here this is more than just a religious event, its a matter of national pride. Reporter this week politicians tried to draft off the popes popularity. Like John Paul Francis has the ability to stand apart from the leader he is standing next to i skill he will rely on in the u. S. Hes got his own talking and hes not going to be swayed by the politic of the united states. Thats not going to keep him away from saying what he thinks needs to be said here. Reporter a message embraced by many here. We have these feelings inside we want to express out. And i think this pope feels the same way. Reporter a native son on a mission to change the world. Anne thompson, nbc news quito. A wild night in denver. Lightning so intense that our denver affiliate kusa was knocked off the air for a few minutes. They had to improvise showing video and footage from ipods. Things were back to normal with only a few minor issues. Serena williams captured the womens title at wimbledon, becoming the oldest woman ever to win a major tournament. More from nbcs joe fryer. Reporter with a hardfought victory on centre court, she scored a title only she can win, serena slam. Oh, man, it is really a great feeling. Reporter just what is the serena slam . It means she has won the last four pages. U. S. Open Australian Open french open and wimbledon. I honestly wouldnt have thought last year after winning the u. S. Open i would win the serena slam at all. Reporter in her career she has now served up 21 majors in all, one shy of the open era record. Even when she doesnt play her best she competes better than anybody on the planet. And thats what has gotten her here. Thats why she is chasing history reporter we have been watching serena and big sister venus since they were teenage prodigies. Today at 33 years old, serena is the oldest woman in tenniss open era to ever win a singles title. To fans she is stronger than ever. Everything looks like a battle for her and she wins. Reporter for all her success, one thing she has not achieved the prestigious grand slam winning all four majors in the same calendar year. The last player to do that stephy graph in 1988. Now williams has a chance at the u. S. Open in september. She will try to turn her serena slam into a true grand slam. She would tie grafs records for the most 22. She realizes she could be the greatest of all time. Not only that she should be the greatest of all time. Reporter 33 might be ancient in tennis years, burr Serena Williams appears far from down. Theyll be packing the stands later in new york this summer. When nightly news returns on this saturday a battle in the west against an epidemic of fires being deliberately set later, after a series of attacks, a California City o if you have moderate to severe plaque psoriasis. Isnt it time to let the real you shine through . Introducing otezla apremilast. Otezla is not an injection or a cream. Its a pill that treats plaque psoriasis differently. Some people who took otezla saw 75 clearer skin after 4 months. And otezlas prescribing information has no requirement for routine lab monitoring. Dont take otezla if you are allergic to any of its ingredients. Otezla may increase the risk of depression. Tell your doctor if you have a history of depression or suicidal thoughts, or if these feelings develop. Some people taking otezla reported weight loss. Your doctor should monitor your weight and may stop treatment. Side effects may include diarrhea nausea, upper respiratory tract infection, and headache. 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With high potency vitamin b12. And more vitamin d. Tonight in our series burning up were going inside the war against wildfires in the west. Not just fighting the fires themselves but cracking down on those who deliberately set them. Nbcs Hallie Jackson with that story tonight from california. Reporter the wildfire in the town burned so fast it destroyed a house every 30 seconds. Oh, my god. This is it. Reporter including sues. It was sad. It was very devastating. Reporter the person who started this fire was charged with arson. And while the suspect pleaded guilty to lesser charges, more than 1,000 other wildfires in california just last year were set on purpose. Blame the record drought, extreme wind spreading the fire as fast as ever. But blazes dont begin by themselves. In california one in every five wildfires starts intentionally set by an arsonist. Jennifer hunts them down. Not just a fire chief but a Law Enforcement officer. One of 150 trained at a special state academy in how to trace a fire to its source and figure out whether it was an accident or not. Why do you all do it . Some people do it for monetary gain. Some people do it for the thrill. They do it because its a way of asserting themselves in a powerful manner when their lives are powerless. To burn houses to kill people reporter people like the firefighters on engine 57. All five died in the esperanza fire in 2006. The person who set it convicted for murder. Arsons consequences sometimes deadly. Wildfires always devastating. We dont have a water spigot. Reporter but here they are determined to rebuild. The anger has turned into that want to get our town back to try to get back to the new normal. Reporter a Community Stronger than a single cry, their homes gone but not their hope. Hallie jackson, nbc news, San Bernardino california. Up next superstars on nobody told me to expect it. Intercourse thats painful due to menopausal changes. 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Bottom of the seventh, the giants john launching a tworun homer out of the park. The ball takes a bounce lands in the bay, and so does this very dedicated fan. Theres the splash. He goes home with the ball. Next time however, he may want to bring his glove along with his swim trunks. The coyote has always been a symbol of the wild. Thats changing as the animals move in on more Populated Areas out west. In irvine california many attacks have people on edge. We have more tonight. Reporter a walk in the park now comes with a warning. There is a coyote around to there. Reporter in Southern California a father arms himself with a stick. This woman carries pepper spray after a frightening encounter with a coyote. It started circling us and was being very aggressive. Reporter by nature they are known to be timid animals. But residents say they fear caye its more than the coyotes fear them. Jessie smith is relieved her baby wasnt with her when she encountered one. I put my hands in the air, yelled stamped my feet. He wasnt backing off reporter since may, this small area of irvine has seen four coyote attacks. Each more brazen. One near a park a playground. Last sunday a small child attacked in a garage. And a 7yearold scratched inside her Family Living room. Thankfully none of the injuries were life threatening. I moved out here because its more rural. I didnt expect to be kicking coyotes down the street reporter the ongoing drought isnt helping pushing wild animals into Populated Areas in search of food and water. Across the country, in chicago, this fitted with a gps by national geographic, carefully avoids traffic. And in the concrete jungles of new york city they have been spotted from manhattan to queens. Experts save coyotes are changing because society haslett them get too close. They are basically changing because we have changed. Reporter these days people are more likely to post a picture online than to rush and scare them away. 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We have the mortar and the original glass. Reporter to many here it is no surprise vanning is gaining traction all over again. Vanning started in the 70s as a way to customize and party in a mobile fashion. Its enjoying this great renaissance i think for some of the same reasons reporter david brooks saw his first van seven years ago and fell in love. Vanning can be appreciated by all ages. Youre out seeing the country and the sights. If i had a van it would be pink and black. Reporter the van is a staple of american pop culture. I hope we took the right turn back there. Reporter remember scoobydoos mystery machine . Or a teams van . Or spicolis van in fast times at ridgemont high. Its not just an event. Its a family reunion. Reporter the reunion ends this weekend but the spirit lives on. Absolutely going to be back next year. Reporter as vanners keep rolling down the road. John yang nbc news. Nice wheels. Thats nbc nightly news for this saturday. Ill see you tomorrow morning and back here tonight. For all of us here at announcer the following program is sponsored by st. Jude childrens research hospital. I was just absolutely terrified. Is this gonna be the last time i might see my daughter . And the doctor said, go directly to st. Jude. They said, if we hadnt got her there, she maybe wouldve had two more days to live. When you have cancer, you have to have a lot of hope. Without the help of st. Jude, he wouldnt be here today. It could happen to anybody that you love. Tomorrow were gonna wake up and another parent is gonna hear, your child has cancer. Hi. Im marlo thomas. And i want you to meet some of the bravest, most inspiring children in the world. These kids are fighting for