Voxelotor Improves Cerebral Hemodynamic Parameters in Pediatric Sickle Cell Disease

Voxelotor decreases oxygen extraction fraction and cerebral blood flow towards levels observed in healthy children.

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Erinm Buckley , ,Wallaceh Coulter Department Of Biomedical Engineering ,Georgia Institute Of Technology Erinm Buckley ,Drug Administration ,Emory University ,Georgia Institute Of Technology ,Buckley ,Georgia Institute ,Biomedical Engineering ,Cerebral Blood Flow ,Oxygen Extraction ,Pediatric Sickle Cell ,Magn Reson ,Drug Evaluation ,